WEEK 4Trimester 1Baby: Poppy seed

Implantation and Blastocyst Differentiation

Estimated Length0.1 cm
Estimated Weight0.01 g

Fetal Morphogenesis & Anatomy Highlights

  • Blastocyst completes implantation into the secretory endometrium.
  • Trophoblast differentiates into cytotrophoblast and syncytiotrophoblast, secreting beta-hCG.
  • Embryonic disc divides into epiblast and hypoblast (bilaminar embryonic disc).
  • Early uteroplacental circulation initiates via maternal lacunae.
Clinician Perspective • Physiological & Screening Protocols

Maternal Physiological Adaptations

Corpus luteum produces high progesterone under hCG stimulation to maintain decidua before the luteal-placental shift.

Expected Clinical Symptoms

Missed menstrual periodMild uterine cramping (implantation)Breast tenderness & fullnessEarly fatigue

Clinical Investigations & Screening Schedule

  • Home urine pregnancy test (detects beta-hCG >= 25 mIU/mL).
  • Confirmation quantitative serum beta-hCG if history of ectopic pregnancy or recurrent loss.
  • Baseline bloodwork: CBC, Blood group & Rh antibody screen, Rubella, Varicella, Hep B, HIV, Syphilis (VDRL), Urine culture.
Upcoming Visit Horizon: First prenatal visit usually booked between 8 and 10 weeks gestation unless early dating ultrasound or high risk.