WEEK 16Trimester 2Baby: Avocado

Musculoskeletal Ossification & Fine Motor Movement

Estimated Length11.6 cm
Estimated Weight100 g

Fetal Morphogenesis & Anatomy Highlights

  • Skeleton undergoing active endochondral ossification, visible on ultrasound.
  • Eyes face forward and begin slow conjugate movements; retinal vasculature forming.
  • Scalp hair patterning established; fine lanugo hair covers the skin to hold vernix caseosa.
  • Fetal heart pumps roughly 28 liters of blood per day through the fetoplacental unit.
Clinician Perspective • Physiological & Screening Protocols

Maternal Physiological Adaptations

Fundus is palpable midway between pubic symphysis and umbilicus. Circulating plasma volume expanding by 30-40%.

Expected Clinical Symptoms

Energy rebound ('golden trimester')Nosebleeds or nasal congestion (rhinitis of pregnancy)Appetite increaseMild round ligament pain with position changes

Clinical Investigations & Screening Schedule

  • Maternal Serum Quad Screen if first trimester screening was missed.
  • Maternal Serum Alpha-Fetoprotein (MSAFP) for open neural tube defects (optimal window 15w0d to 20w6d).
  • Fetal heart Doppler check in clinic (normal: 110–160 bpm).
Upcoming Visit Horizon: Book 18–22 week detailed anatomical ultrasound.